Month: February 2025
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Humane Genomics
We recently announced our first biotech investment at USV in a company called Humane Genomics. They engineer viruses that can be made to selectively infect different kinds of cells. To start, they’re focused on viruses that kill cancer cells (“oncolytic viruses”). The first oncolytic viral therapy to be approved in…
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Against The End of History of Venture Capital
I’ve written previously about the deep tech opportunity. While lean software startups have been a great place to invest venture capital over the last thirty years, I believe we’re living through a shift where future returns in venture capital will be more driven by companies that engage in fundamental innovation.…
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Cactos
The dramatic reduction in the cost of solar energy means we can cheaply produce clean power– but only when the sun is out. Batteries are a natural companion to solar, capable of soaking up surplus energy when the sun is shining, and using that energy or feeding it back to the…
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Presto
Electric vehicles are a prime example of how electricity will be used in more complex ways as we electrify everything to reduce carbon emissions. As batteries, they enable shifting electricity usage in time, and as vehicles, they enable shifting usage in space. At USV, we’ve been interested in facilitating this…
Matthew Mandel 